They are more suited for fine-tuning body composition in already-lean individuals
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However, the majority of recently developed SARMs have non-steroidal structures, which may be based on [22]: Aryl-propionamide (andarine, ostarine, RAD140) Bicyclic hydantoin (BMS-564,929) Quinolinones and tetrahydroquinoline analogs Benizimidazole, imidazolopyrazole, indole, and pyrazoline derivaties Aniline, diaryl aniline, and bezoxazepinones derivatives Regardless of structure, all SARMs work by interacting with the androgen receptors (ARs) in specific tissues, i.e., selectively, rather than activating ARs throughout the body
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These adaptions drive tumor proliferation, survival, and migration by fundamentally reshaping cellular biological characteristics [4]